Coronaviruses, most recently SARS-CoV-2 which causes COVID-19, are a major target for vaccine and drug design.
This database is an up-to-date reference for SARS-CoV-2, SARS-CoV, and MERS-CoV structures, focused on antibody recognition, host receptor binding, drug targeting, and diversity. It contains a comprehensive annotated set of structures of coronavirus proteins, updated weekly from the Protein Data Bank. It was developed and is maintained by the Pierce Lab at the Institute for Bioscience and Biotechnology Research and the University of Maryland.
Tools and resources used by this site include the Protein Data Bank, NCBI, NGL Viewer, Weblogo, Plotly, Tabulator and Rosetta. The front page virus image is from the CDC, and original site template (heavily modified by us) is from Templatemo.
If you use CoV3D in your work, please cite us:
Gowthaman R, Guest JD, Yin R, Adolf-Bryfogle J, Schief WR, Pierce BG. (2020) CoV3D: a database of high resolution coronavirus protein structures. Nucleic Acids Research, In Press. Article PubMed
Questions, comments, or suggestions can be sent to Dr. Ragul Gowthaman, ragul (at) umd.edu.